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Welcome to Mad Gender Science! This wiki contains everything a budding mad (gender) scientist needs to further their work. Specifically, this is a resource for transgender people to educate themselves about the biology underlying transition and developmental sex differentiation, and to advance trans healthcare ourselves!

Resources for people beginning their physical transition
Finding access to hormones or blockers through a medical provider is the often first order of business. You may be surprised at how accessible hormones can be, and things are much safer when medical professionals are engaged. If you are young, you may want to consider hitting the snooze button on puberty using GnRH agonists/antagonists, while making the decision to start hormone therapy.

In many parts of the world medical providers refuse to provide hormones or have arcane restrictions (*cough* the Netherlands), or may be financially out of reach (*cough* USA.) In these cases, you may consider going DIY.

Natural transition options: Pharmaceutical transition options:
 * FTM natural transition guide
 * MTF natural transition guide
 * MTF hormone replacement therapy guide
 * FTM hormone replacement therapy guide
 * Non-binary hormone therapy guide (highly experimental!)

In either event, please stay safe! Blood tests and staying safe has information on monitoring your hormone levels.

This isn't medical advice! I don't want you to get hurt, and DIY is a serious decision. Do your own research and double-check the info here; there's no "one size fits all" treatment plan and you're taking your life in your own hands. Lastly, if you show an endocrinologist that you're serious about DIY, they may relent and prescribe you hormones as a harm reduction measure.

Resources for self-education
You can start reading about the biological mechanisms involved in sex differentiation. HRT plays with these mechanisms, so it's important to know how they function. Timeline of sexual development (masculine) or Timeline of sexual development (feminine) is a good starting point for understanding how all this happened to us.

Resources for Mad SCIENCE!
Mwahahahahaa! If you're interested in the biological aspects of all this stuff, see Papers for a collection of useful papers organized by topic. A great way to start learning is to fill in articles on the Wishlist, using information from the papers (and Mabel will thank you eternally for contributing to her project!) I'm also researching a bunch of moonshot science projects like cellular reprogramming, alternative HRT regimens and computer programs.

Contact
I can be reached on tumblr, or under the usernames mabel/esmerelda on ##transdrugs on the freenode IRC server (irc.freenode.net.) I also check my talk page.