5α-Reductase inhibitor



5α-Reductase (5-AR) is the enzyme in the cytosol of cells that converts Testosterone into Dihydrotestosterone (DHT), which is ~100x more potent. However, this isn't 5-AR's only job - it also metabolizes neurosteroids in the brain, and in general reduces (replaces Oxygen with Hydrogen) on the 5α position on any steroid.