Pharmaceutical feminizing HRT

Generally speaking, every MTF HRT regimen will include an anti-androgen, to suppress the effects of testosterone on the body, alongside some form of estrogen and some form of progesterone. However, depending on health condition and the effects you're going for, your needs may vary. This is a collection of a few HRT regimens I've found interesting or representative.

Basic: Spironolactone + 17β-estradiol
Spironolactone serves as the anti-androgen. It binds to the Androgen Receptor:Androgen Receptor (AR), preventing Testosterone/DHT from activating the receptor, but as an 'antagonist'/'partial agonist' it doesn't "turn on" the AR to a significant degree. Estradiol, also known as E2, is one of the body's natural estrogens. It activates the Estrogen receptors.

Resources

 * WPATH Standards of Care contains "diagnostic criteria", medical treatment recommendations, timelines etc.
 * Hormones: a guide for MTFs is a great, human-readable guide on what to expect from hormonal transition.