Enzalutamide
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Drug class: | Nonsteroidal antiandrogen |
Brand names: | Xtandi |
Enzalutamide is a nonsteroidal antiandrogen, similar to bicalutamide. It has a higher binding affinity to the androgen receptor than bicalutamide.
Safety
Unlike bicalutamide, enzalutamide is associated with an increased risk of seizures. This may be due to off-target GABAA inhibition. See Wikipedia:Enzalutamide#Central adverse effects for more information.