Breast development in transgender women

From Mad Gender Science!

Feminizing hormone therapy induces breast development in transgender women. Estrogens are responsible for the process.

A number of studies have assessed breast development in response to feminizing hormone therapy in transgender women.[1][2][3][4][5][6]


  1. Wierckx, K., Gooren, L., & T'sjoen, G. (2014). Clinical review: Breast development in trans women receiving cross‐sex hormones. The journal of sexual medicine, 11(5), 1240-1247.
  2. de Blok, C. J. M., Klaver, M., Wiepjes, C. M., Nota, N. M., Heijboer, A. C., Fisher, A. D., ... & den Heijer, M. (2017). Breast Development in Transwomen After One Year of Cross-sex Hormone Therapy: Results of A Prospective Multicenter Study. The Journal of Clinical Endocrinology & Metabolism.
  3. Tack, L. J., Heyse, R., Craen, M., Dhondt, K., Bossche, H. V., Laridaen, J., & Cools, M. (2017). Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents. The Journal of Sexual Medicine, 14(5), 747-757.
  4. Meyer, W. J., Finkelstein, J. W., Stuart, C. A., Webb, A., Smith, E. R., Payer, A. F., & Walker, P. A. (1981). Physical and hormonal evaluation of transsexual patients during hormonal therapy. Archives of sexual behavior, 10(4), 347-356.
  5. Meyer, W. J., Webb, A., Stuart, C. A., Finkelstein, J. W., Lawrence, B., & Walker, P. A. (1986). Physical and hormonal evaluation of transsexual patients: a longitudinal study. Archives of sexual behavior, 15(2), 121-138.
  6. Dittrich, R., Binder, H., Cupisti, S., Hoffmann, I., Beckmann, M. W., & Mueller, A. (2005). Endocrine treatment of male-to-female transsexuals using gonadotropin-releasing hormone agonist. Experimental and clinical endocrinology & diabetes, 113(10), 586-592.